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The Effect of Patellar Taping on Some Landing Characteristics During Counter Movement Jumps in Healthy Subjects

Cámara, Jesús; Díaz, Francisco; Anza, María Soledad; Mejuto, Gaizka; Puente, Asier; Iturriaga, Gorka; Fernández, Juan-Ramón
Fonte: Asist Group Publicador: Asist Group
Tipo: Artigo de Revista Científica
Publicado em 01/12/2011 Português
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The aim of the present study was to determine the effect of patellar taping (PT) on landing characteristics of the vertical ground reaction force (VGRF) and on flight time during a counter movement jump (CMJ). Eleven healthy male subjects (age: 31.1 ± 4.2 years) volunteered for the study. Each subject performed six CMJs under two different jumping conditions: with PT and without PT (WPT). The order of the two conditions was randomized. All of the measured variables had fair-to-good reliability (intra-class correlation coefficient > 0.75). When we compared the PT and WPT groups, we did not find a significant difference in the magnitude of the first (F1) and second (F2) peaks of the VGRF. We also did not find a significant difference in the time to production of these peaks (T1 and T2), and the time to stabilization (TTS) (p < 0. 05). Furthermore, the flight time was similar in the two groups (0.475 ± 0.046 and 0.474 ± 0.056 s, respectively, for PT and WPT). These results suggest that PT does not jeopardize performance during CMJ. Furthermore, it also does not soften the VGRF generated during the landing, indicating that PT may be of limited utility in preventing injuries associated with this type of movement.

The Tumor Targeted Superantigen ABR-217620 Selectively Engages TRBV7-9 and Exploits TCR-pMHC Affinity Mimicry in Mediating T Cell Cytotoxicity

Hedlund, Gunnar; Eriksson, Helena; Sundstedt, Anette; Forsberg, Göran; Jakobsen, Bent K.; Pumphrey, Nicholas; Rödström, Karin; Lindkvist-Petersson, Karin; Björk, Per
Fonte: Public Library of Science Publicador: Public Library of Science
Tipo: Artigo de Revista Científica
Publicado em 23/10/2013 Português
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The T lymphocytes are the most important effector cells in immunotherapy of cancer. The conceptual objective for developing the tumor targeted superantigen (TTS) ABR-217620 (naptumomab estafenatox, 5T4Fab-SEA/E-120), now in phase 3 studies for advanced renal cell cancer, was to selectively coat tumor cells with cytotoxic T lymphocytes (CTL) target structures functionally similar to natural CTL pMHC target molecules. Here we present data showing that the molecular basis for the anti-tumor activity by ABR-217620 resides in the distinct interaction between the T cell receptor β variable (TRBV) 7-9 and the engineered superantigen (Sag) SEA/E-120 in the fusion protein bound to the 5T4 antigen on tumor cells. Multimeric but not monomeric ABR-217620 selectively stains TRBV7-9 expressing T lymphocytes from human peripheral blood similar to antigen specific staining of T cells with pMHC tetramers. SEA/E-120 selectively activates TRBV7-9 expressing T lymphocytes resulting in expansion of the subset. ABR-217620 selectively triggers TRBV7-9 expressing cytotoxic T lymphocytes to kill 5T4 positive tumor cells. Furthermore, ABR-217620 activates TRBV7-9 expressing T cell line cells in the presence of cell- and bead-bound 5T4 tumor antigen. Surface plasmon resonance analysis revealed that ABR-217620 binds to 5T4 with high affinity...

The “voice” has it: screen reader adoption and switching behavior among vision impaired persons in India

McCarthy, Ted; Pal, Joyojeet; Cutrell, Edward
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em //2013 Português
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We present results from a mixed methods study of screen reader use and switching behavior among people with vision impairments in India. We examine loyalty and experimentation with screen readers and find that the main drivers of adoption for early users differ significantly from the factors that drive continued use by advanced users. We discuss the factor that emerges as one of the strongest stated drivers of early adoption, TTS “voice” quality, particularly a “human-sounding voice” as one of the key features differentiating free/open source (FOSS) products from more expensive proprietary products. While the initial preferences are driven by voice quality, application support becomes more important over time as users speed up their sound settings and become more comfortable with the resultant non-human-sounding speech. We discuss these findings from two theoretical perspectives – first, through the application of the economics of behavior switching, and second, vis-à-vis novice and expert approaches toward new product adoption. We argue that these findings further our understanding of initial user comfort related to assistive technology adoption, and the impact of early technology choices on long-term technology switching behavior.

The Tertiary Origin of the Allosteric Activation of E. coli Glucosamine-6-Phosphate Deaminase Studied by Sol-Gel Nanoencapsulation of Its T Conformer

Zonszein, Sergio; Álvarez-Añorve, Laura I.; Vázquez-Núñez, Roberto J.; Calcagno, Mario L.
Fonte: Public Library of Science Publicador: Public Library of Science
Tipo: Artigo de Revista Científica
Publicado em 02/05/2014 Português
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The role of tertiary conformational changes associated to ligand binding was explored using the allosteric enzyme glucosamine-6-phosphate (GlcN6P) deaminase from Escherichia coli (EcGNPDA) as an experimental model. This is an enzyme of amino sugar catabolism that deaminates GlcN6P, giving fructose 6-phosphate and ammonia, and is allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P). We resorted to the nanoencapsulation of this enzyme in wet silica sol-gels for studying the role of intrasubunit local mobility in its allosteric activation under the suppression of quaternary transition. The gel-trapped enzyme lost its characteristic homotropic cooperativity while keeping its catalytic properties and the allosteric activation by GlcNAc6P. The nanoencapsulation keeps the enzyme in the T quaternary conformation, making possible the study of its allosteric activation under a condition that is not possible to attain in a soluble phase. The involved local transition was slowed down by nanoencapsulation, thus easing the fluorometric analysis of its relaxation kinetics, which revealed an induced-fit mechanism. The absence of cooperativity produced allosterically activated transitory states displaying velocity against substrate concentration curves with apparent negative cooperativity...

Neural correlates of moderate hearing loss: time course of response changes in the primary auditory cortex of awake guinea-pigs

Huetz, Chloé; Guedin, Maud; Edeline, Jean-Marc
Fonte: Frontiers Media S.A. Publicador: Frontiers Media S.A.
Tipo: Artigo de Revista Científica
Publicado em 28/04/2014 Português
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Over the last decade, the consequences of acoustic trauma on the functional properties of auditory cortex neurons have received growing attention. Changes in spontaneous and evoked activity, shifts of characteristic frequency (CF), and map reorganizations have extensively been described in anesthetized animals (e.g., Noreña and Eggermont, 2003, 2005). Here, we examined how the functional properties of cortical cells are modified after partial hearing loss in awake guinea pigs. Single unit activity was chronically recorded in awake, restrained, guinea pigs from 3 days before up to 15 days after an acoustic trauma induced by a 5 kHz 110 dB tone delivered for 1 h. Auditory brainstem responses (ABRs) audiograms indicated that these parameters produced a mean ABR threshold shift of 20 dB SPL at, and one octave above, the trauma frequency. When tested with pure tones, cortical cells showed on average a 25 dB increase in threshold at CF the day following the trauma. Over days, this increase progressively stabilized at only 10 dB above control value indicating a progressive recovery of cortical thresholds, probably reflecting a progressive shift from temporary threshold shift (TTS) to permanent threshold shift (PTS). There was an increase in response latency and in response variability the day following the trauma but these parameters returned to control values within 3 days. When tested with conspecific vocalizations...

Outcomes of Patients With Metastatic Renal Cell Carcinoma and End-Stage Renal Disease Receiving Dialysis and Targeted Therapies: A Single Institution Experience

Shetty, Aditya V.; Matrana, Marc R.; Atkinson, Bradley J.; Flaherty, Amber L.; Jonasch, Eric; Tannir, Nizar M.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
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Data are limited regarding outcomes in patients with end-stage renal disease (ESRD) and metastatic renal cell carcinoma (mRCC) receiving targeted therapy. We retrospectively identified patients with mRCC and ESRD treated at the University of Texas M.D. Anderson Cancer Center from 2002 to 2012. Fourteen patients were identified with a median number of targeted therapies (TTs) per patient of 3 (range, 1–4). Outcomes in patients with mRCC and ESRD were similar to those reported in patients with normal kidney function.

Incremental cost per newly diagnosed HIV infection (NDHI): routine (RTS), targeted (TTS), and current clinical practice testing strategies (CPTS)

Gomez-Ayerbe, Cristina; Jesús Pérez Elías, María; Muriel, Alfonso; Pérez Elías, Pilar; Cano, Agustina; Diaz, Alberto; Moreno, Ana; Luis Casado, Jose; Santos, Cristina; Martinez-Colubi, María; Uranga, Almudena; Dronda, Fernando; Moreno, Santiago
Fonte: International AIDS Society Publicador: International AIDS Society
Tipo: Artigo de Revista Científica
Publicado em 02/11/2014 Português
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The Krüppel-associated box repressor domain induces reversible and irreversible regulation of endogenous mouse genes by mediating different chromatin states

Ying, Yue; Yang, Xingyu; Zhao, Kai; Mao, Jifang; Kuang, Ying; Wang, Zhugang; Sun, Ruilin; Fei, Jian
Fonte: Oxford University Press Publicador: Oxford University Press
Tipo: Artigo de Revista Científica
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The Krüppel-associated box (KRAB) domain is a transcription repression module from the largest family of transcriptional regulators encoded by higher vertebrates. We developed a drug-controllable regulation system based on an artificial KRAB-containing repressor (tTS) that targets the endogenous Hprt gene to explore the regulatory mechanism and molecular basis of KRAB-containing regulators within the context of an endogenous gene in vivo. We show that KRAB can mediate irreversible and reversible regulation of endogenous genes in mouse that is dependent on embryonic developmental stage. KRAB-induced stable DNA methylation within the KRAB binding region during the early embryonic stage, resulting in irreversible gene repression. In later stages, KRAB mainly induced de-acetylation and methylation of histone, resulting in reversible gene repression. Thus, we have characterized the KRAB-mediated regulation system within the context of an endogenous gene and multiple spatiotemporal ranges, thereby providing a basis for identifying the function of KRAB-containing regulators and aiding development of novel KRAB-based gene regulation tools in vivo.

Generation of a conditionally self-eliminating HAC gene delivery vector through incorporation of a tTAVP64 expression cassette

Kononenko, Artem V.; Lee, Nicholas C.O.; Liskovykh, Mikhail; Masumoto, Hiroshi; Earnshaw, William C.; Larionov, Vladimir; Kouprina, Natalay
Fonte: Oxford University Press Publicador: Oxford University Press
Tipo: Artigo de Revista Científica
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Human artificial chromosome (HAC)-based vectors represent an alternative technology for gene delivery and expression with a potential to overcome the problems caused by virus-based vectors. The recently developed alphoidtetO-HAC has an advantage over other HAC vectors because it can be easily eliminated from cells by inactivation of the HAC kinetochore via binding of chromatin modifiers, tTA or tTS, to its centromeric tetO sequences. This provides a unique control for phenotypes induced by genes loaded into the HAC. The alphoidtetO-HAC elimination is highly efficient when a high level of chromatin modifiers as tetR fusion proteins is achieved following transfection of cells by a retrovirus vector. However, such vectors are potentially mutagenic and might want to be avoided under some circumstances. Here, we describe a novel system that allows verification of phenotypic changes attributed to expression of genes from the HAC without a transfection step. We demonstrated that a single copy of tTAVP64 carrying four tandem repeats of the VP16 domain constitutively expressed from the HAC is capable to generate chromatin changes in the HAC kinetochore that are not compatible with its function. To adopt the alphoidtetO-HAC for routine gene function studies...

Miscibility and Viscoelastic Properties of Acrylic Polyhedral Oligomeric Silsesquioxane-Poly(methyl methacrylate) Blends

Kopesky, Edward T.; Haddad, Timothy S.; McKinley, Gareth H.; Cohen, Robert E.
Fonte: MIT - Massachusetts Institute of Technology Publicador: MIT - Massachusetts Institute of Technology
Tipo: Pré-impressão Formato: 805252 bytes; application/pdf
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We investigate the miscibility of acrylic polyhedral oligomeric silsesquioxanes (POSS) [characteristic size d ≈ 2 nm] and poly(methyl methacrylate)(PMMA) in order to determine the effect of well-dispersed POSS nanoparticles on the thermomechanical properties of PMMA. Two different acrylic POSS species (unmodified and hydrogenated) were blended separately with PMMA at volume fractions up to φ = 0.30. Both POSS species have a plasticizing effect on PMMA by lowering the glass transition temperature Tg and decreasing the melt-state linear viscoelastic moduli measured in small amplitude oscillatory shear flow. The unmodified acrylic-POSS has better miscibility with PMMA than the hydrogenated form, approaching complete miscibility for loadings φ < 0.10. At a loading φ = 0.05, the unmodified acrylic POSS induces a 4.9°C decrease in the Tg of PMMA, far less than the 17.4°C decrease in the glass transition temperature observed in a blend of 5 vol% dioctyl phthalate (DOP) in PMMA; however, the decrease in the glass transition temperature per added plasticizer molecule is nearly the same in the unmodified acrylic-POSS-PMMA blend compared with the DOP-PMMA blend. Time-temperature superposition (TTS) was applied successfully to the storage and loss moduli data and the resulting shift factors were correlated with a significant increase in free volume of the blends. The fractional free volume f0 = 0.046 for PMMA at T0 = 170°C while for a blend of 5 vol% unmodified acrylic-POSS in PMMA f0 = 0.057...

Agricultura familiar e economia solidária: as experiências em gestão de bens comuns e inserções nos mercados por organizações rurais do estado de Minas Gerais

Melo, Ana Paula Gomes de
Fonte: Mestrado em Administração; UFLA; brasil; Departamento de Administração e Economia Publicador: Mestrado em Administração; UFLA; brasil; Departamento de Administração e Economia
Tipo: Dissertação
Publicado em 11/09/2015 Português
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Tne present research consists in a study about the partnership economy which develops in the family agricumiral extent in the state ofMinas Gerais. It also seeks to understand the ways and concepts offàrmers on their experiences in eelleetíve undeftaking. The present werk also directs tts attention to the historical forms builtto deal with the ordinary goods management, as well asthe concem in understanding the insertion forms on the market, the established Telation among the mediator organizations and in estimating the economical and non economical profits - material and non material outcome - resulted from collective experiences. rt is a multi-case study, in which 15 collective undertaking experiences were researched on the Alto Vale do Jequitinhonha, Vale do Mucuri and Noroeste, Tegions of CAV - Centro de Agricultura Alternativa Vicente Nica, ARMICOPA - Associação Regional do Mucuri de Cooperação dos Pequenos Agricultores and Cáritas Diocesana de Paracatu, respectively. Itwas observed that the social relation characteristics, the solidarity links pre-existent on the groups influence on working out the criteria and management norms, as -well as the elaboration of internai participation mechanisms and on the relation with externai organizations. Moreover...

Using Sonic Enhancement to Augment Non-Visual Tabular Navigation

Cofino, Jonathan M; Barreto, Armando
Fonte: FIU Digital Commons Publicador: FIU Digital Commons
Tipo: Artigo de Revista Científica Formato: application/pdf
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More information is now readily available to computer users than at any time in human history; however, much of this information is often inaccessible to people with blindness or low-vision, for whom information must be presented non-visually. Currently, screen readers are able to verbalize on-screen text using text-to-speech (TTS) synthesis; however, much of this vocalization is inadequate for browsing the Internet. An auditory interface that incorporates auditory-spatial orientation was created and tested. For information that can be structured as a two-dimensional table, links can be semantically grouped as cells in a row within an auditory table, which provides a consistent structure for auditory navigation. An auditory display prototype was tested. Sixteen legally blind subjects participated in this research study. Results demonstrated that stereo panning was an effective technique for audio-spatially orienting non-visual navigation in a five-row, six-column HTML table as compared to a centered, stationary synthesized voice. These results were based on measuring the time- to-target (TTT), or the amount of time elapsed from the first prompting to the selection of each tabular link. Preliminary analysis of the TTT values recorded during the experiment showed that the populations did not conform to the ANOVA requirements of normality and equality of variances. Therefore...

Using sonic enhancement to augment non-visual tabular navigation

Cofino, Jonathan
Fonte: FIU Digital Commons Publicador: FIU Digital Commons
Tipo: Artigo de Revista Científica
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More information is now readily available to computer users than at any time in human history; however, much of this information is often inaccessible to people with blindness or low-vision, for whom information must be presented non-visually. Currently, screen readers are able to verbalize on-screen text using text-to-speech (TTS) synthesis; however, much of this vocalization is inadequate for browsing the Internet. An auditory interface that incorporates auditory-spatial orientation was created and tested. For information that can be structured as a two-dimensional table, links can be semantically grouped as cells in a row within an auditory table, which provides a consistent structure for auditory navigation. An auditory display prototype was tested.^ Sixteen legally blind subjects participated in this research study. Results demonstrated that stereo panning was an effective technique for audio-spatially orienting non-visual navigation in a five-row, six-column HTML table as compared to a centered, stationary synthesized voice. These results were based on measuring the time- to-target (TTT), or the amount of time elapsed from the first prompting to the selection of each tabular link. Preliminary analysis of the TTT values recorded during the experiment showed that the populations did not conform to the ANOVA requirements of normality and equality of variances. Therefore...

Stress corrosion cracking of rock bolts

Gamboa, E.; Villalba, E.; Atrens, A.
Fonte: Australian Fracture Group; Australia Publicador: Australian Fracture Group; Australia
Tipo: Conference paper
Publicado em //2004 Português
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The aim of this research was to understand the Stress Corrosion Cracking (SCC) of rock bolts. The laboratory tests produced fracture surfaces similar to those from service. The fracture surface has the following types: TTS (Tearing Topography Surface) at the origin of the SCC, CIS (Corrugated Irregular Surface) and qMVC (quasi Micro Void Coalescence) at the interface with the final fast fracture. The experimental study elucidated the environmental conditions leading to rock bolt SCC, and was used to determine the threshold stress and the threshold potential. A hydrogen embrittlement mechanism is proposed.; Erwin Gamboa, Ernesto Villalba and Andrej Atrens

Perinatal mortality and mode of delivery in monochorionic diamniotic twin pregnancies ≥32 weeks of gestation: a multicentre retrospective cohort study; Perinatal mortality and mode of delivery in monochorionic diamniotic twin pregnancies >/=32 weeks of gestation: a multicentre retrospective cohort study

Hack, K.; Derks, J.; Elias, S.; van Mameren, F.; Koopman-Esseboom, C.; Mol, B.; Lopriore, E.; Schaap, A.; Arabin, B.; Duvekot, J.; Go, A.; Wieselmann, E.; Eggink, A.; Willekes, C.; Vandenbussche, F.; Visser, G.
Fonte: Wiley Publicador: Wiley
Tipo: Artigo de Revista Científica
Publicado em //2011 Português
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Objective:  To study perinatal mortality rates in a cohort of 465 monochorionic (MC) twins without twin-twin transfusion syndrome (TTS) born at 32 weeks of gestation or later since reported interauterine fetal death (IUFD) rates >32 weeks of gestations in the literature vary, leading to varying recommendations on the optimal timing of delivery, and to investigate the relation between perinatal mortality and mode of delivery. Design:  Multicentre retrospective cohort study. Setting:  Ten perinatal referral centres in the Netherlands. Population:  All MC twin pregnancies without TTTS delivered at ≥32 weeks of gestation between January 2000 and December 2005. Methods:  The medical records of all MC twin pregnancies without TTTS delivered at the ten perinatal referral centres in the Netherlands between January 2000 and December 2005 were reviewed. Main outcome measures:  Perinatal mortality in relation to gestational age and mode of delivery at ≥32 weeks of gestation. Results:  After 32 weeks of gestation, five out of 930 fetuses died in utero and there were six neonatal deaths (6 per 1000 infants). In women who delivered ≥37 weeks, perinatal mortality was 7 per 1000 infants. Trial of labour was attempted in 376 women and was successful in 77%. There were three deaths in deliveries with a trial of labour (8 per 1000 deliveries)...

Assessment of the noise-protective action of the olivocochlear efferents in humans

Wolpert, Stephan Matthias; Heyd, Andreas; Wagner, Wolfgang
Fonte: Basel : Karger Publicador: Basel : Karger
Tipo: Artikel
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TESTING DISK-LOCKING IN NGC 2264

Cauley, P. Wilson; Johns-Krull, Christopher M.; Hamilton, Catrina M.; Lockhart, Kelly
Fonte: Universidade Rice Publicador: Universidade Rice
Tipo: Artigo de Revista Científica
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We test analytic predictions from different models of magnetospheric accretion, which invoke disk-locking, using stellar and accretion parameters derived from models of low-resolution optical spectra of 36 T Tauri stars (TTSs) in NGC 2264 (age ∼3Myr). Little evidence is found for models that assume purely dipolar field geometries; however, strong support is found in the data for a modified version of the X-wind model which allows for non-dipolar field geometries. The trapped flux concept in the X-wind model is key to making the analytic predictions which appear supported in the data. By extension, our analysis provides support for the outflows predicted by the X-wind as these also originate in the trapped flux region. In addition, we find no support in the data for accretion-powered stellar winds from young stars. By comparing the analysis presented here of NGC 2264 with a similar analysis of stars in Taurus (age ∼1–2 Myr), we find evidence that the equilibrium interaction between the magnetic field and accretion disk in TTS systems evolves as the stars grow older, perhaps as the result of evolution of the stellar magnetic field geometry. We compare the accretion rates we derive with accretion rates based on U-band excess...

Applicability of DoDAF to the conversion of a crane ship to host a ballistic missile defense test radar and telemetry system

Lash, Michael E.
Fonte: Monterey, California. Naval Postgraduate School Publicador: Monterey, California. Naval Postgraduate School
Tipo: Tese de Doutorado
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Currently, all Missile Defense Agency (MDA) instrumentation radars are land-based at Reagan Test Site (RTS) in the Marshall Islands and the Pacific Missile Range Facility (PMRF) on the Hawaiian island of Kauai. The dependency on land-based radars produces significant gaps in radar coverage of planned ballistic missile defense system (BMDS) tests. The S.S. Beaver State is a former cargo ship that was converted to a crane ship. The purpose of a crane ship is to unload/load other ships at ports with inadequate facilities. When the Beaver State was converted to a crane ship, three large cranes were installed. The size of the ship and generators make the Beaver State suitable to host the first X-Band Test Radar (XTR-1) and the second Transportable Telemetry System (TTS-2). There are five major efforts in the conversion process: 1) Ship reactivation; 2) Modification of the ship to host the primary sensors, the adjunct systems, and the respective operators; 3) Installation and integration of the primary sensors and adjunct systems; 4) Development, installation, and certification of the communications system; and 5) Coast Guard certification. This thesis will review the history of the modification design and communications system development aspects of this conversion process...

OBELISK : portal web de gestión de usuarios de una centralita de VoIP

Gómez-Pimpoyo Fernández, Ana Isabel
Fonte: Universidade Carlos III de Madrid Publicador: Universidade Carlos III de Madrid
Tipo: info:eu-repo/semantics/bachelorThesis; info:eu-repo/semantics/masterThesis Formato: application/octet-stream; application/octet-stream; application/pdf
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OBELISK es una interface gráfica, desarrollada como página Web, que tiene como función principal simplificar el alta de usuarios en una centralita de voz IP, en este caso en Asterisk. Otras funciones destacables son: • Poder programar llamadas a una hora determinada a un conjunto de contactos del usuario. • Realizar llamadas desde la aplicación Web sin necesidad de tener un software adicional instalado. • Permite al usuario gestionar su agenda de contactos. Para poder ofrecer estas funcionalidades se hace uso de la centralita de Voz IP Asterisk y del programa TTS (Text To Speech, texto a voz) Festival entre otros. ______________________________________________________________________________; OBELISK is a graphic interface developed as a Web page whose main function is to simplify users’ register in an IP voice central, in this case Asterisk. Other important points are: • The ability to make schedule calls in a specific moment to contacts’ group. • To make calls from a Web application without additional software. • For users to manage their contact lists. These functionalities are offered by Asterisk (Voice IP central) and by the Festival Text To Speech program, among others.

Evaluating the use of speech technologies in the classroom: The APEINTA Project

Jiménez, Javier; Revuelta, Pablo; Moreno, Lourdes; Iglesias, Ana
Fonte: Association for the Advancement of Computing in Education (AACE) Publicador: Association for the Advancement of Computing in Education (AACE)
Tipo: info:eu-repo/semantics/acceptedVersion; info:eu-repo/semantics/conferenceObject; info:eu-repo/semantics/conferenceObject Formato: application/pdf
Publicado em //2010 Português
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APEINTA (Spanish acronym for Proposal Aiming for an Inclusive Education based on Assistive Technology) is a Spanish educational project that aims for inclusive education for every student of all abilities in and outside the classroom. The APEINTA project is focused in two main inclusive proposals: One In the classroom and the other one Outside the classroom. This paper is focused on a subjective evaluation of the In the classroom proposal, where Automatic Speech Recognition (ASR) and Text to Speech (TTS) technologies have been used in order to avoid communication barriers among teacher and students. The project has been evaluated during different classes in 3rd course of Computer Science degree at the Carlos III University of Madrid, and during a talk in the ACAPPS (Federation of Families and Deaf People of Catalonia) Congress.; Proceeding of: World Conference on Educational Multimedia, Hypermedia & Telecommunications, ED-MEDIA 2010