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Estudo da convergência no método de elementos finitos aplicado a dispositivos eletromagnéticos não lineares.; Survey on the convergence of non-linear finite element method applied to electromagnetic devices in two-dimension.
Uso de matriz extracelular (Matrigel®) para estabelecimento de cultivo de células-tronco embrionárias de suínos e caracterização da expressão de moléculas associadas à pluripotência; Use of extracellular matrix (Matrigel®) for establishment of porcine embryonic stem cells and expression characterization of plurpotency related molecules
Avaliação de custo e eficácia de métodos e critérios de teste baseado em Máquinas de Estados Finitos; Evaluate of cost and effectiveness of FSM based testing methods and criteria
Sobre o acoplamento fluido-casca utilizando o método dos elementos finitos; On fluid-shell coupling using the finite element method
Estudo da distribuição de temperatura na região de formação de cavacos usando método dos elementos finitos; Study of temperature distribution in the formation of chips using finite element method
Acionamento por motor elétrico de rotor apoiado por mancal magnético com controle uniaxial.; Driving electric motor using rotor with 1-DOF magnetic bearing.
Ajuste de modelos numericos usando funções de resposta em frequencia
Ajuste de modelos de estruturas acopladas por juntas mecanicas usando funções de resposta em frequencia e sintese dos modos dos componentes
Produção da bananeira 'Prata anã'(AAB) em função de diferentes doses e fontes de potássio
Contribuição ao estudo das propriedades dos materiais cimentícios reforçados com fibras de vidro (Glass Fibre Reinforced Cement - GRC); Contribution to the study of properties of glass fibre reinforced cement - GRC
Signal Transduction and Transcription Factor Modification during Reactivation of Epstein-Barr Virus from Latency
The flow-volume loop: reproducibility of air and helium-based tests in normal subjects
Micro-electro-fluidic grids for nematodes: A lens-less, image-sensor-less approach for on-chip tracking of nematode locomotion
Transcription of the human beta enolase gene (ENO-3) is regulated by an intronic muscle-specific enhancer that binds myocyte-specific enhancer factor 2 proteins and ubiquitous G-rich-box binding factors.
Reemergence of Macrolide Resistance in Pharyngeal Isolates of Group A Streptococci in Southwestern Pennsylvania
Doxycycline reduces the migration of tuberous sclerosis complex-2 null cells - effects on RhoA-GTPase and focal adhesion kinase
Integrating Multiple Evidence Sources to Predict Adverse Drug Reactions Based on a Systems Pharmacology Model
Herramienta para la solución de EDP sobre dominios generales en 2-D mediante métodos adaptativos
Unification of Dark Matter and Dark Energy in a Modified Entropic Force Model
Mechanisms of Molecular Chaperone Surface Binding and Endocytosis: Insights into the Molecular Basis for GRP94 Immune Function
Extracellular GRP94 can elicit both innate and adaptive immune responses by interacting with endocytic and signaling receptors on professional antigen presenting cells (pAPCs). CD91 was the first receptor proposed to facilitate GRP94-mediated immune responses. Using a GRP94 affinity matrix, a CD91 fragment was isolated from the detergent-solubilized membranes of a pAPC cell line. It was then demonstrated that CD91 ligands could inhibit GRP94-mediated peptide cross-presentation, suggesting that CD91 played a critical role in this process. While these studies implied that CD91 could function as a GRP94 endocytic receptor, later works suggested that CD91 may not recognize GRP94 at the cell surface. These opposing observations have lead to a significant controversy surrounding the identity of CD91 as an endocytic receptor for GRP94. Because the ability of CD91 to directly mediate GRP94 surface binding and uptake has not been established, the studies included in this dissertation have focused on evaluating the ability of CD91 to facilitate three processes that are necessary for GRP94-mediated peptide cross-presentation: surface binding, internalization, and processing.
These studies utilized a recombinantly-expressed N-terminal domain of GRP94 (GRP94.NTD)...