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Endovascular repair of an aorto-iliac aneurysm succeeded by kidney transplantation; Tratamento endovascular de aneurisma aorto-ilíaco sucedido por transplante renal

DALIO, Marcelo Bellini; BREDARIOLI, Matheus; JOVILIANO, Edwaldo Edner; CHERRI, Jesualdo; SUAID, Haylton Jorge; PICCINATO, Carlos Eli
Fonte: Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV) Publicador: Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)
Tipo: Relatório
Português
Relevância na Pesquisa
37.5312%
We present the case of aorto-iliac aneurysm in a patient with chronic renal failure requiring dialysis who were treated with an endovascular stent graft and, later on, submitted to kidney transplantation. A 53-year-old male with renal failure requiring dialysis presented with an asymptomatic abdominal aorto-iliac aneurysm measuring 5.0cm of diameter. He was treated with endovascular repair technique, being used an endoprosthesis Excluder®. After four months, he was successfully submitted to kidney transplantation (dead donor), with anastomosis of the graft renal artery in the external iliac artery distal to the endoprosthesis. The magnetic resonance imaging, carried out 30 days after the procedure, showed a good positioning of the endoprosthesis and adequate perfusion of the renal graft. In the follow-up, the patient presented improvement of nitrogenous waste, good positioning of the endoprosthesis without migration or endoleak. The endovascular repair of aorto-iliac aneurysm in a patient with end-stage renal failure under hemodialysis treatment showed to be feasible, safe and efficient, as it did not prevent the success of the posterior kidney transplantation.; Apresentamos o caso de aneurisma aortoilíaco em um paciente com insuficiência renal crônica dialítica tratado com uma endoprótese vascular...

Urological complication following aortoiliac graft: case report and review of the literature; Complicação urológica após enxerto aorto-ilíaco: relato de caso e revisão de literatura

BORGES, Leonardo Lima; TORRICELLI, Fábio César Miranda; EBAID, Gustavo Xavier; LUCON, Antônio Marmo; Srougi, Miguel
Fonte: Associação Paulista de Medicina - APM Publicador: Associação Paulista de Medicina - APM
Tipo: Relatório
Português
Relevância na Pesquisa
48.140903%
CONTEXT: Ureteral stenosis and ureterohydronephrosis may be serious complications of aortoiliac or aortofemoral reconstructive surgery. CASE REPORT: A 62-year-old female patient presented with a six-month history of left lumbar pain. She was a smoker, and had mild chronic arterial hypertension and Takayasu arteritis. She had previously undergone three vascular interventions. In two procedures, Dacron prostheses were necessary. Excretory urography showed moderate left ureterohydronephrosis and revealed a filling defect in the ureter close to where the iliac vessels cross. This finding was compatible with ureteral stenosis, and the aortoiliac graft may have been the reason for this inflammatory process. The patient underwent laparotomy, which showed that there was a relationship between the ureteral stenosis and the vascular prosthesis. Segmental ureterectomy and end-to-end ureteroplasty with the ureter crossing over the prosthesis anteriorly were performed. There were no complications. The early and late postoperative periods were uneventful. The patient evolved well and the results from a new excretory urogram were normal. We concluded that symptomatic ureterohydronephrosis following aortoiliac graft is a real complication and needs to be quickly diagnosed and treated by urologists.; INTRODUÇÃO: Estenose ureteral e ureterohidronefrose podem ser sérias complicações da cirurgia reconstrutiva aorto-femoral ou aorto-ilíaca. RELATO DE CASO: Uma paciente de 62 anos apresentou-se referindo história de dor lombar a esquerda há seis meses. Ela era fumante...

Tratamento endovascular dos aneurismas da aorta abdominal com anatomia complexa: resultados preliminares com a segunda geração de endoprótese com arcabouço metálico circular; Endovascular treatment of abdominal aortic aneurysms with complex anatomy: preliminary results of the second generation stent graft with a dual-ring design

Metzger, Patrick Bastos; Novero, Eduardo Rafael; Rossi, Fabio Henrique; Moreira, Samuel Martins; Barbato, Heraldo Antônio; Izukawa, Nilo Mitsuru; Marco, Vanessa Luciene Abreu de; Cano, Manoel Nicolas; Kambara, Antonio Massamitsu
Fonte: Sociedade Brasileira de Hemodinâmica e Cardiologia Intervencionista - SBHCI Publicador: Sociedade Brasileira de Hemodinâmica e Cardiologia Intervencionista - SBHCI
Tipo: Artigo de Revista Científica
Português
Relevância na Pesquisa
37.5312%
INTRODUÇÃO: O tratamento endovascular dos aneurismas da aorta abdominal tem revolucionado o tratamento dessa afecção, em decorrência das baixas taxas de morbidade e mortalidade. Apesar dos avanços tecnológicos ocorridos nas endopróteses, ainda existem limitações anatômicas para o emprego da técnica. Este estudo teve por objetivo avaliar os resultados imediatos do tratamento de pacientes portadores de aneurisma da aorta abdominal com anatomia complexa com uma endoprótese de segunda geração. MÉTODOS: Estudo observacional, prospectivo, não-randomizado, realizado em um único centro, em uma série de pacientes submetidos a tratamento endovascular de aneurismas da aorta abdominal infrarrenais complexos, com prótese com arcabouço metálico disposta em anéis (Anaconda - Vascutek, Terumo, Inchinnan, Escócia). Foram avaliados as características clínicas e angiográficas, o sucesso técnico, o sucesso terapêutico, a morbidade e a mortalidade, e a taxa de reintervenção perioperatória. RESULTADOS: Foram analisados, no período de fevereiro de 2010 a dezembro de 2011, 108 pacientes consecutivos portadores de aneurisma da aorta, dos quais 16 eram portadores de aneurisma da aorta abdominal com anatomia complexa tratados com a prótese Anaconda . A média de idade foi de 76 + 7 anos e 75% eram do sexo masculino. Houve sucesso técnico em 94% e êxito terapêutico em 75% dos casos. Ocorreu um óbito no pós-operatório. As complicações perioperatórias mais prevalentes foram sangramento da ferida operatória (2/16) e embolia periférica (2/16). Foram necessárias reintervenções em 12...

"Análise volumétrica da hiperplasia intimal intra-stent em pacientes diabéticos tratados com e sem abciximab" ; Volumetric analysis of in-stent intimal hyperplasia in diabetic patients treated with or without abciximab

Chaves, Áurea Jacob
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 19/07/2004 Português
Relevância na Pesquisa
37.5312%
Noventa e seis pacientes com diabetes melito do tipo 2 foram randomizados para receberem ou não abciximab durante o implante eletivo de stent coronário, com o objetivo de determinar se esse inibidor da glicoproteína IIb/IIIa reduz a hiperplasia intimal intra-stent, avaliada pelo ultra-som intracoronário, aos seis meses de evolução. A análise volumétrica mostrou que o abciximab não reduz o volume de obstrução intra-stent nestes pacientes [41,3% (DP21,0%) versus 40,5% (DP18,3%), p=0,853]. ; Ninety-six type 2 diabetics were randomly assigned to receive abciximab or no abciximab at the time of elective stent implantation to determine whether this IIb/IIIa glycoprotein inhibitor would reduce in-stent intimal hyperplasia, measured by intravascular ultrasound, at 6-month follow-up. Volumetric analysis showed that abciximab was not associated with a reduction of in-stent volume obstruction in diabetic patients [41.3% (DP21.0%) versus 40.5% (DP18.3%), p=0.853).

"Estudo experimental da transmissão da pulsatilidade da endoprótese à parede do aneurisma da aorta após correção endoluminal" ; Pulsatility transmission from endograft to aortic aneurysm wall after endovascular repair : an experimental study

Orra, Hussein Amin
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 26/09/2005 Português
Relevância na Pesquisa
37.931318%
Objetivo: Medir a pulsatilidade da parede do aneurisma de aorta humano antes e depois de sua correção endoluminal. Método: Cinco aneurismas foram submetidos à perfusão pulsátil antes e depois do implante de uma endoprótese. Resultado: o nível da coluna de água oscilou durante a pulsação com variações de 17, 16, 13, 7 e 25 cm antes da colocação da endoprótese. Depois da prótese, a oscilação diminuiu em todos os casos para 13, 12, 9, 3,5 e 23 cm, respectivamente. Conclusão: A pulsação da endoprótese é transmitida à parede do aneurisma ; Objective: To measure the pulsatility of human aortic aneurysms before and after exclusion with endograft. Method: Five aneurysms were submitted to pulsatile perfusion before and after implantation of a bifurcated endograft. Result: The level of the water column oscillated during pulsation, in each case, with an amplitude of 17, 16, 13, 7 and 25 cm before the endograft insertion. After that, the amplitudes dropped to, respectively 13, 12, 9, 3.5 and 23 cm.Conclusion: Pulsation of an endograft is transmitted to the aneurysm wall even in the absence of endoleak

Terapêutica endovascular percutânea na oclusão arterial ilíaca crônica; Percutaneous endovascular therapy of chronic iliac artery occlusion

Carnevale, Francisco Cesar
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 03/09/1999 Português
Relevância na Pesquisa
38.4804%
A revascularização da oclusão arterial ilíaca crônica com implante de endoprótese vascular é uma nova modalidade terapêutica para os pacientes com aterosclerose obliterante das extremidades. Os objetivos deste trabalho são verificar: os resultados clínico e radiológico do tratamento percutâneo com implante de endoprótese vascular nas oclusões arteriais crônicas do território ilíaco; a influência da aterosclerose e seus principais fatores de risco; os principais sintomas clínicos segundo os estágios de Fontaine e o comportamento das endopróteses vasculares, avaliando as permeabilidades primária e secundária. Foram estudados 67 pacientes, com 69 oclusões arteriais ilíacas crônicas, submetidos a intervenção de janeiro de 1992 a dezembro de 1998, por meio de avaliação clínica, Doppler com medida do índice tornozelo/braço e arteriografia dos membros inferiores. As revascularizações arteriais ilíacas foram realizadas sob anestesia local, utilizando-se as endopróteses tipos Wallstent® e Cragg®. O índice de sucesso técnico foi de 97,10%. A mediana do período de internação foi de dois dias e as complicações mais importantes foram tromboses arteriais (2,99%), roturas arteriais (2,99%) e embolia poplítea (1...

Estudo experimental comparativo de implantes arteriais : politetrafluoretileno expandido (PTFE) versus polidimetilsiloxano com reforço de tecido de poliéster; Experimental comparative study of arterial implants - expanded polytetrafluoroethylene (PTFE) versus dimethylpolysiloxane reinforced with polyester fabric

Appolonio, Fernanda
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 30/05/2014 Português
Relevância na Pesquisa
58.61351%
INTRODUÇÃO: Os enxertos vasculares sintéticos disponíveis atualmente apresentam baixos índices de patência, quando utilizados na revascularização de vasos de pequeno calibre, e possuem resultados inferiores quando comparados ao uso de veias autólogas em derivações infrageniculares. Nova prótese de pequeno calibre confeccionada em silicone (polidimetilsiloxano, PDMS) com reforço de tecido de poliéster foi desenvolvida e comparada à prótese de PTFE. OBJETIVOS: Analisar, em modelo experimental em coelhos, o tubo de PDMS como material para prótese vascular e compará-lo a prótese de PTFE. MÉTODOS: Quarenta coelhos foram submetidos a interposição na aorta infrarrenal de próteses de 4mm de diâmetro, sendo 20 animais com PDMS e 20 com PTFE (grupo controle). Foi medido o tempo de clampeamento e realizada arteriografia retrógrada da aorta para avaliar a patência das próteses. Para avaliar a endotelização das próteses foi realizada microscopia eletrônica de maneira amostral pareada. RESULTADOS: Vinte e cinco animais (62,5%) não apresentaram intercorrências pós-operatórias; oito (20%) morreram precocemente e sete (17,5%) ficaram paraplégicos no pós-operatório imediato (e foram sacrificados), sendo que esses animais não foram incluídos nas análises de patência. Não foi observada diferença entre os grupos quanto à evolução com complicações pós-operatórias (p=0...

Hiperplasia intimal após implante de stent em aorta de suínos submetidos à hiper-homocisteinemia induzida

França, Luis Henrique Gil
Fonte: Universidade Federal do Rio Grande do Sul Publicador: Universidade Federal do Rio Grande do Sul
Tipo: Tese de Doutorado Formato: application/pdf
Português
Relevância na Pesquisa
48.080283%
A hiperplasia intimal é uma complicação comum após o implante de stent em artérias periféricas e a influência da homocisteína neste processo ainda é desconhecida. O objetivo deste estudo é comparar o espessamento intimal em aorta de suínos submetidos à hiper-homocisteinemia induzida com suínos normais, após implante de stents auto-expansíveis de nitinol. Foram utilizados 18 suínos da raça Macau, com peso médio de 30 kg. Os animais foram divididos aleatoriamente em dois grupos: o primeiro, grupo C (controle), foi alimentado com dieta normal e o outro, grupo M (metionina), recebeu dieta rica em metionina para induzir hiper-homocisteinemia durante 30 dias. Os stents utilizados para o experimento foram os auto-expansíveis, de nitinol, com 25 milímetros de comprimento e diâmetro final de oito milímetros. Foram realizadas dosagens de colesterol, triglicerídeos, colesterol HDL e homocisteína plasmática em ambos os grupos. A adequação das medidas do stent em relação às dimensões da artéria aorta dos suínos e a sua perviedade, após o implante, foram confirmadas mediante realização de arteriografias seletivas. Trinta dias após o implante do stent, os animais foram submetidos à eutanásia e as peças enviadas para exame anatomopatológico. O exame histológico mostrou intensa hiperplasia intimal no grupo controle e placas formadas por macrófagos espumosos com pouca hiperplasia intimal no grupo metionina. A análise morfométrica digital revelou maior hiperplasia intimal no grupo C em relação ao grupo M. Não ocorreram mudanças significativas nas dosagens de colesterol...

Position Statement on Bioresorbable Vascular Scaffolds in Portugal

Campante Teles, R; Pereira, H; Cyrne de Carvalho, H; Patrício, L; Santos, R; Baptista, J; Pipa, J; Farto e Abreu, P; Faria, H; Sousa Ramos, M; Gama Ribeiro, V; Martins, D; Almeida, M
Fonte: Sociedade Portuguesa de Cardiologia Publicador: Sociedade Portuguesa de Cardiologia
Tipo: Artigo de Revista Científica
Publicado em //2013 Português
Relevância na Pesquisa
37.931318%
BACKGROUND: Bioresorbable vascular scaffolds (BVS) were recently approved for percutaneous coronary intervention in Europe. The aim of this position statement is to review the information and studies on available BVS, to stimulate discussion on their use and to propose guidelines for this treatment option in Portugal. METHODS AND RESULTS: A working group was set up to reach a consensus based on current evidence, discussion of clinical case models and individual experience. The evidence suggests that currently available BVS can produce physiological and clinical improvements in selected patients. There are encouraging data on their durability and long-term safety. Initial indications were grouped into three categories: (a) consensual and appropriate - young patients, diabetic patients, left anterior descending artery, long lesions, diffuse disease, and hybrid strategy; (b) less consensual but possible - small collateral branches, stabilized acute coronary syndromes; and (c) inappropriate - left main disease, tortuosity, severe calcification. CONCLUSION: BVS are a viable treatment option based on the encouraging evidence of their applicability and physiological and clinical results. They should be used in appropriate indications and will require technical adaptations. Outcome monitoring and evaluation is essential to avoid inappropriate use. It is recommended that medical societies produce clinical guidelines based on high-quality registries as soon as possible.

Position Statement on Bioresorbable Vascular Scaffolds in Portugal

Campante Teles, R; Pereira, H; Cyrne de Carvalho, H; Patrício, L; Santos, R; Baptista, J; Pipa, J; Farto e Abreu, P; Faria, H; Sousa Ramos, M; Gama Ribeiro, V; Martins, D; Almeida, M
Fonte: Sociedade Portuguesa de Cardiologia Publicador: Sociedade Portuguesa de Cardiologia
Tipo: Artigo de Revista Científica
Publicado em //2013 Português
Relevância na Pesquisa
37.931318%
BACKGROUND: Bioresorbable vascular scaffolds (BVS) were recently approved for percutaneous coronary intervention in Europe. The aim of this position statement is to review the information and studies on available BVS, to stimulate discussion on their use and to propose guidelines for this treatment option in Portugal. METHODS AND RESULTS: A working group was set up to reach a consensus based on current evidence, discussion of clinical case models and individual experience. The evidence suggests that currently available BVS can produce physiological and clinical improvements in selected patients. There are encouraging data on their durability and long-term safety. Initial indications were grouped into three categories: (a) consensual and appropriate - young patients, diabetic patients, left anterior descending artery, long lesions, diffuse disease, and hybrid strategy; (b) less consensual but possible - small collateral branches, stabilized acute coronary syndromes; and (c) inappropriate - left main disease, tortuosity, severe calcification. CONCLUSION: BVS are a viable treatment option based on the encouraging evidence of their applicability and physiological and clinical results. They should be used in appropriate indications and will require technical adaptations. Outcome monitoring and evaluation is essential to avoid inappropriate use. It is recommended that medical societies produce clinical guidelines based on high-quality registries as soon as possible.

Surgarcane biopolymer patch in femoral artery angioplasty on dogs

Aguiar,José Lamartine de Andrade; Lins,Esdras Marques; Marques,Silvio Romero de Barros; Coelho,Antônio Roberto de Barros; Rossiter,Renata de Oliveira; Melo,Roberto José Vieira de
Fonte: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia Publicador: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/01/2007 Português
Relevância na Pesquisa
38.4804%
PURPOSE: The objective of this study was to evaluate the use of the sugarcane biopolymer membrane in femoral artery patch angioplasty on dogs. METHODS: Eight dogs were submitted to bilateral femoral artery patch angioplasty with a sugarcane biopolymer membrane patch on one side and e-PTFE patch on the contralateral side. This research was performed at Experimental Surgical Research Laboratory of the Centro de Ciências da Saúde at Universidade Federal de Pernambuco. The dogs were submitted to a new surgery at 180 days after the patch angioplasty in order to harvest the femoral artery. All the animals were evaluated by: clinical examination, measure of femoral artery diameter, arteriogram and Doppler fluxometry. Yet the material harvested was sent to histological study. Each animal served as its own control. RESULTS: In all vessels of both groups there were no cases of infection, aneurysm formation, rupture or pseudoaneurysm formation and thrombosis. In both groups it was observed a chronic inflammatory reaction with lymphocytes, neutrophils and fibrosis in the outer surface of the patches. It was observed fibrosis in the inner surfaces of all the patches. In e-PTFE patches occurred invasion by fibroblasts. CONCLUSION: The sugarcane biopolymer membrane can be used as a patch in femoral artery angioplasty on dogs.

Urological complication following aortoiliac graft: case report and review of the literature

Borges,Leonardo Lima; Torricelli,Fábio César Miranda; Ebaid,Gustavo Xavier; Lucon,Antônio Marmo; Srougi,Miguel
Fonte: Associação Paulista de Medicina - APM Publicador: Associação Paulista de Medicina - APM
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/05/2010 Português
Relevância na Pesquisa
48.140903%
CONTEXT: Ureteral stenosis and ureterohydronephrosis may be serious complications of aortoiliac or aortofemoral reconstructive surgery. CASE REPORT: A 62-year-old female patient presented with a six-month history of left lumbar pain. She was a smoker, and had mild chronic arterial hypertension and Takayasu arteritis. She had previously undergone three vascular interventions. In two procedures, Dacron prostheses were necessary. Excretory urography showed moderate left ureterohydronephrosis and revealed a filling defect in the ureter close to where the iliac vessels cross. This finding was compatible with ureteral stenosis, and the aortoiliac graft may have been the reason for this inflammatory process. The patient underwent laparotomy, which showed that there was a relationship between the ureteral stenosis and the vascular prosthesis. Segmental ureterectomy and end-to-end ureteroplasty with the ureter crossing over the prosthesis anteriorly were performed. There were no complications. The early and late postoperative periods were uneventful. The patient evolved well and the results from a new excretory urogram were normal. We concluded that symptomatic ureterohydronephrosis following aortoiliac graft is a real complication and needs to be quickly diagnosed and treated by urologists.

The effect of cardiopulmonary bypass in coronary artery bypass surgeries (on-pump versus off-pump) on erectile function and endothelium-derived nitric oxide levels

Canguven,Onder; Albayrak,Selami; Selimoglu,Ahmet; Balaban,Muhsin; Sasmazel,Ahmet; Baysal,Ayse
Fonte: Sociedade Brasileira de Urologia Publicador: Sociedade Brasileira de Urologia
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/12/2011 Português
Relevância na Pesquisa
47.73665%
PURPOSE: To investigate the effects of on-pump and off-pump coronary artery bypass grafting (CABG) on the erectile function and endothelium-derived nitric oxide (eNO) levels. MATERIALS AND METHODS: Twenty-eight consecutive patients were randomized into two groups depending on use of cardiopulmonary bypass in CABG surgery. The erectile function was evaluated by using the IIEF-5 questionnaire. The plasma eNO levels were determined at baseline and after reactive hyperemia before and after surgery. Blood was collected in one minute after cuff deflation from the radial artery on the same side. RESULTS: After CABG surgery the mean IIEF-5 score increased insignificantly over baseline from 14.8 to 15.8 (p = 0.29) and 12.4 to 14.3 (p = 0.11) after on-pump and off-pump CABG surgeries, respectively. The baseline plasma NO levels before surgery were 18.16 ± 7.63 nmol/L in on-pump and 21.76 ± 11.08 nmol/L in off-pump CABG. After reactive hyperemia the plasma NO levels were 22.14 ± 10.52 nmol/L in on-pump and 21.49 ± 9.13 nmol/L in off-pump CABG before the surgery. The difference in the plasma NO levels before surgery was not significant (p = 0.51). Two hours after surgery, the difference of the plasma NO levels at baseline (24.44 ± 12.31on-pump and 20.58 ± 6.74 nmol/L off-pump CABG) and after reactive hyperemia (35.55 ± 23.54 nmol/L on-pump and 23.00 ± 15.40 nmol/L off-pump CABG) were not significantly different from each other (p = 0.11). CONCLUSIONS: Patients who had on-pump or off-pump CABG surgeries had higher IIEF-5 scores. Nevertheless...

Smooth Muscle Cell Alignment and Phenotype Control by Melt Spun Polycaprolactone Fibers for Seeding of Tissue Engineered Blood Vessels

Agrawal, Animesh; Lee, Bae Hoon; Irvine, Scott A.; An, Jia; Bhuthalingam, Ramya; Singh, Vaishali; Low, Kok Yao; Chua, Chee Kai; Venkatraman, Subbu S.
Fonte: Hindawi Publishing Corporation Publicador: Hindawi Publishing Corporation
Tipo: Artigo de Revista Científica
Português
Relevância na Pesquisa
37.73665%
A method has been developed to induce and retain a contractile phenotype for vascular smooth muscle cells, as the first step towards the development of a biomimetic blood vessel construct with minimal compliance mismatch. Melt spun PCL fibers were deposited on a mandrel to form aligned fibers of 10 μm in diameter. The fibers were bonded into aligned arrangement through dip coating in chitosan solution. This formed a surface of parallel grooves, 10 μm deep by 10 μm across, presenting a surface layer of chitosan to promote cell surface interactions. The aligned fiber surface was used to culture cells present in the vascular wall, in particular fibroblasts and smooth muscle cells. This topography induced “surface guidance” over the orientation of the cells, which adopted an elongated spindle-like morphology, whereas cells on the unpatterned control surface did not show such orientation, assuming more rhomboid shapes. The preservation of VSMC contractile phenotype on the aligned scaffold was demonstrated by the retention of α-SMA expression after several days of culture. The effect was assessed on a prototype vascular graft prosthesis fabricated from polylactide caprolactone; VSMCs aligned longitudinally along a fiberless tube...

Long-term results of femorotibial bypass with vein or polytetrafluoroethylene

Sayers, R.; Raptis, S.; Berce, M.; Miller, J.
Fonte: Universidade de Adelaide Publicador: Universidade de Adelaide
Tipo: Artigo de Revista Científica
Publicado em //1998 Português
Relevância na Pesquisa
37.73665%
BACKGROUND: This was a retrospective review of the long-term results of femorotibial bypass using autologous vein and polytetrafluoroethylene (PTFE) over 24 years. METHODS: Some 518 patients who underwent 635 femorotibial bypass grafts were studied. Outcome measures analysed included primary and secondary graft patency, limb salvage rates and death. RESULTS: Overall primary and secondary graft patencies were 62 and 67 per cent respectively at 12 months, and 44 and 48 per cent at 24 months. For vein grafts, the primary and secondary patencies were 63 and 66 per cent at 12 months, and 54 and 56 per cent at 24 months. For PTFE grafts, the primary and secondary patencies were 48 and 54 per cent at 12 months, and 31 and 37 per cent at 24 months. Limb salvage and patient survival rates were 81 and 84 per cent at 12 months, and 73 and 74 per cent at 24 months. Primary and secondary graft patencies for vein were significantly better than for PTFE (P = 0.0001). There was no difference in patency between reversed and in situ grafts. CONCLUSION: Femorotibial bypass can produce excellent long-term results. Vein remains the conduit of choice but in the absence of vein acceptable results can be achieved with PTFE.; Sayers, R D ; Raptis, S ; Berce...

Preoperative prediction of sepsis after aortic surgery

Cowled, P.; Fitridge, R.
Fonte: Blackwell Science Asia Publicador: Blackwell Science Asia
Tipo: Artigo de Revista Científica
Publicado em //2010 Português
Relevância na Pesquisa
38.4804%
Prudence A. Cowled, Robert A. Fitridge

Proximal endovascular blood flow shunt for thoracoabdominal aortic aneurism without total aortic clamping

Espinosa,Gaudencio; Tavares,Rivaldo; Fonseca,Felippe; Collares,Alessandra; Lopes,Marina; Fonseca,Jose Luis; Steffan,Rafael
Fonte: Colégio Brasileiro de Cirurgiões Publicador: Colégio Brasileiro de Cirurgiões
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/06/2015 Português
Relevância na Pesquisa
47.73665%

Clinical Outcome and Morphologic Determinants of Mural Thrombus in Abdominal Aortic Endografts

Oliveira, N; Bastos Gonçalves, F; Hoeks, S; Ten Raa, S; Ultee, K; Rouwet, E; Hendriks, J; Verhagen, H
Fonte: Elsevier Publicador: Elsevier
Tipo: Artigo de Revista Científica
Publicado em /06/2015 Português
Relevância na Pesquisa
39.370942%
OBJECTIVE:Endograft mural thrombus has been associated with stent graft or limb thrombosis after endovascular aneurysm repair (EVAR). This study aimed to identify clinical and morphologic determinants of endograft mural thrombus accumulation and its influence on thromboembolic events after EVAR. METHODS: A prospectively maintained database of patients treated by EVAR at a tertiary institution from 2000 to 2012 was analyzed. Patients treated for degenerative infrarenal abdominal aortic aneurysms and with available imaging for thrombus analysis were considered. All measurements were performed on three-dimensional center-lumen line computed tomography angiography (CTA) reconstructions. Patients with thrombus accumulation within the endograft's main body with a thickness >2 mm and an extension >25% of the main body's circumference were included in the study group and compared with a control group that included all remaining patients. Clinical and morphologic variables were assessed for association with significant thrombus accumulation within the endograft's main body by multivariate regression analysis. Estimates for freedom from thromboembolic events were obtained by Kaplan-Meier plots. RESULTS: Sixty-eight patients (16.4%) presented with endograft mural thrombus. Median follow-up time was 3.54 years (interquartile range...

Tratamiento endovascular de aneurisma aórtico abdominal: resultados en 80 pacientes consecutivos

Valdés E,Francisco; Mertens M,Renato; Krämer Sch,Albrecht; Bergoeing R,Michel; Mariné M,Leopoldo; Canessa B,Roberto; Huete G,Alvaro; Vergara G,Jeanette; Valdebenito C,Magaly; Rivera D,Dixiana
Fonte: Sociedad Médica de Santiago Publicador: Sociedad Médica de Santiago
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/10/2006 Português
Relevância na Pesquisa
47.73665%
Background: Endovascular repair of abdominal aortic aneurysms (AAA) avoids laparotomy, shortens hospital stay and reduces morbidity and mortality related to surgical repair, allowing full patient recovery in less time. Aim: To report short and long term results of endovascular repair of AAA in 80 consecutive patients treated at our institution. Patients and Methods: Between September 1997 and February 2005, three women and 77 men with a mean age 73.6±7.7 years with AAA 5.8±1.0 cm in diameter, were treated. The surgical risk of 38% of patients was grade III according to the American Society of Anesthesiologists classification. Each procedure was performed in the operating room, under local or regional anesthesia, with the aid of digital substraction angiography. The endograft was deployed through the femoral artery (83.7% bifurcated, 16.3% tubular graft). A femoro-femoral bypass was required in 11.3% of cases. Follow-up included a spiral CT scan at 1, 6 and 12 months postoperatively, and then annually. Results: Endovascular repair was successfully completed in 79/80 patients (98.7% technical success). The procedures lasted 147±71 min. Length of stay in the observation unit was 20.6±13.5 h. Blood transfusion was required in 10%. Sixty two percent of the patients were discharged before 72 h. One patient died 8 days after surgery due to a myocardial infarction (1.3%). During follow-up (3-90 months)...

Tratamiento endovascular del trauma de aorta descendente

Mertens M,Renato; Valdés E,Francisco; Krämer Sch,Albrecht; Bergoeing R,Michel; Zalaquett S,Ricardo; Baeza P,Cristián; Morán V,Sergio; Irarrázaval L,Manuel; Becker R,Pedro; Huete G,Alvaro; Vergara G,Jeannette; Valdebenito G,Magaly
Fonte: Sociedad Médica de Santiago Publicador: Sociedad Médica de Santiago
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/04/2005 Português
Relevância na Pesquisa
47.93132%
Background: Mortality of traumatic aortic lesions is over 80%. A group of those who survive, develop a chronic pseudo aneurism, usually asymptomatic, that is detected during imaging studies. Since conventional surgical treatment of traumatic aortic lesions has a great mortality, endovascular treatment has been used as an alternative treatment in the last decade. Aim: To report our experience with endovascular treatment of traumatic aortic lesions. Patients and methods: Report of seven patients aged 22 to 65 years, with traumatic aortic lesions. Under general anesthesia an endovascular prosthesis was inserted through the femoral artery. Results: No complications were observed in the postoperative period, and after a follow up ranging from 4 to 40 months, no endoleaks or other complications have been detected. Conclusions: Endovascular treatment of traumatic aortic lesions has good immediate and midterm results