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Growth of very low birth weight infants fed with milk from a human milk bank selected according to the caloric and protein value

APRILE, Marisa Matta; FEFERBAUM, Rubens; ANDREASSA, Nerli; LEONE, Claudio
Fonte: Faculdade de Medicina / USP Publicador: Faculdade de Medicina / USP
Tipo: Artigo de Revista Científica
Português
Relevância na Pesquisa
47.47979%
OBJECTIVE: To describe growth and clinical evolution of very low birth weight infants fed during hospital stay with milk from a human milk bank according to the caloric-protein value. METHOD: Forty very low birth weight infants were included: 10 were fed milk from their own mothers (GI), and 30 were fed human milk bank > 700 cal/L and 2 g/dL of protein. Growth curves were adjusted using nonlinear regression to the measured growth parameters. RESULTS: full enteral diet was reached in 6.3 days by GI and in 10.8 by GII; a weight of 2 kg was reached in 7.3 weeks for GI and in 7.8 for GII. In GI, 3/10 (33.3%) and in GII, 7/30 (23.3%) developed sepsis. Necrotizing enterocolitis did not occur in GI, but in 3/30 (10.0%) in GII. GI presented with urinary calcium > 4 mg/L in 1/10 (10.0%), urinary phosphorus (Pu) <1 mg/L in 10/10 (100%), and Ca/Cr >0.6 ratio in 1/10 (10.0%) of the cases; in GII, no children presented alterations of the urinary calcium or the Ca and Cr ratio, and Pu was <1 mg/L in 19/30 (63.3%). In terms of growth the 50th percentile for GI was a weight gain of 12.1 g/day (GI) vs. 15.8 g/day (GII), a length gain of 0.75 cm/week (GI) vs. 1.02 cm/week (GII), and a head circumference gain of 0.74 cm/week (GI) vs. 0.76 cm/week (GII). CONCLUSIONS: Human milk bank allowed a satisfactory growth and good clinical evolution for very low birth weight infants.

Concentrações de vitamina A no leite humano e características socioeconômicas e nutricionais maternas: resultados de estudos brasileiros; Vitamin A in human milk and socioeconomic and maternal nutritional factors: some results of Brazilian studies

OLIVEIRA, Julicristie Machado de; OLIVEIRA, Natália Sanchez; BERGAMASCHI, Denise Pimentel
Fonte: Instituto de Medicina Integral Prof. Fernando Figueira Publicador: Instituto de Medicina Integral Prof. Fernando Figueira
Tipo: Artigo de Revista Científica
Português
Relevância na Pesquisa
47.454897%
OBJETIVOS: agregar e discutir os resultados de estudos realizados no Brasil que avaliaram a concentração de vitamina A no leite materno. FONTES DOS DADOS: foram pesquisadas as bases LILACS, Banco de Teses da Capes, SciELO (Scientific Electronic Library), e Plataforma Lattes -seção de produção científica. As palavras-chaves utilizadas foram: gestantes, lactante, concentração de vitamina A no leite humano, Brasil. As buscas foram realizadas em 2006 e atualizadas em março de 2008. Foram incluídos todos os estudos localizados. SÍNTESE DOS DADOS: foram localizados 14 estudos, publicados entre 1988 e 2008, heterogêneos quanto ao tamanho da amostra, fase do leite, período do dia da coleta e método de determinação das concentrações de vitamina A. Foram descritas concentrações médias de vitamina A no leite humano entre 0,62 e 4,50 µmol/L. CONCLUSÕES: não houve consenso sobre a relação entre concentração de vitamina A no leite humano e vitamina A dietética, estado nutricional materno, características obstétricas e demográficas e duração da gestação. Sugere-se que estudos futuros utilizem, amostras de leite maduro, coletadas aleatoriamente ao longo dos diferentes períodos do dia, e a utilização do high performance liquid chromatography - HPLC - como método de determinação de vitamina A.; OBJECTIVES: to compile the results of Brazilian studies that investigated the vitamin A content of human milk. SOURCES: the searches were performed at LILACS...

Crescimento de recém-nascidos de muito baixo peso alimentados com leite de banco de leite humano selecionado segundo o valor calórico e protéico; Growth of very low birth weight infants fed with milk from a human bank selected according to the caloric and protein value

Aprile, Marisa da Matta
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 29/11/2006 Português
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Objetivo: Descrever o crescimento e a evolução clínico laboratorial de recém-nascidos de muito baixo peso (RNMBP) alimentados com leite de banco de leite humano (BLH) segundo o valor calórico e protéico durante a internação e no 6 o mês de idade gestacional corrigida (IGC). Métodos: foram incluídos no estudo 40 RNMBP sem restrição do crescimento intra-útero, divididos em 2 grupos.Grupo I (GI) constituído por 10 RNMBP alimentados com o leite da própria mãe e Grupo II (GII) com 30 RNMBP alimentados com pelo menos 60% de leite de BLH escolhido segundo o valor calórico e protéico. Durante a internação foram analisadas a aceitação e progressão alimentar, as intercorrências clínicas (incidência de sepse, enterocolite necrosante e displasia broncopulmonar) dosados cálcio, fósforo (no soro e urina), uréia e creatinina e Hb / Hct. Construíram-se curvas de crescimento a partir dos dados relativos ao peso, comprimento e perímetro cefálico sendo estabelecidas as equações de regressão não linear que melhor se ajustavam aos dados dos parâmetros de crescimento individuais para cada RNMBP. Resultados: O início da dieta enteral foi, em média, de 1, 2 dias para o G I e 1, 3 dias para o GII e a recuperação do peso de nascimento foi...

The influence of sardine consumption on the omega-3 fatty acid content of mature human milk

Patin, Rose V.; Vítolo, Márcia R.; Valverde, Mara A.; Carvalho, Patrícia O.; Pastore, Gláucia M.; Lopez, Fábio Ancona
Fonte: Universidade Estadual Paulista Publicador: Universidade Estadual Paulista
Tipo: Artigo de Revista Científica Formato: 63-69
Português
Relevância na Pesquisa
47.39628%
Objectives: The purpose of this study was to investigate what effect the ingestion of sardines, rich in omega-3 series polyunsaturated fatty acids, has on the composition of breastmilk. Methods: This was a prospective study of 31 nursing mothers under observation at the Hospital Guilherme Álvaro. Each was given 2 kg of fresh sardines twice with a 15-day interval. Milk was sampled and a 24-hour dietary recall questionnaire was applied on days 0, 15 and 30. Milk was assayed for fatty acid content by gas chromatography. Statistical analysis of the results was performed using nonparametric tests with significance set at p < 0.05. Results: The results demonstrate that the nutritional intake of the nursing mothers was adequate at all three sample points. With regard to the omega-3 series fatty acid content of the breastmilk, it was observed that regular consumption and shorter intervals between ingestion and milk collection resulted in higher concentrations of docosapentaenoic acid and docosahexaenoic acid at 15 and 30 days into the study. Fatty acids from the omega-3 and omega-6 series exhibited a significant correlation, r 2 was 0.58 and 0.59 at 15 and 30 days, respectively. Conclusion: These results suggest that incorporating fish into the diets of nursing mother during lactation...

Vitamin E concentration in human milk and associated factors: a literature review,

Lima,Mayara S.R.; Dimenstein,Roberto; Ribeiro,Karla D.S.
Fonte: Sociedade Brasileira de Pediatria Publicador: Sociedade Brasileira de Pediatria
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/10/2014 Português
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^a Objective: To systematize information about vitamin E concentration in human milk and the variables associated with this composition in order to find possible causes of deficiency, supporting strategies to prevent it in postpartum women and infants. Source: Studies published between 2004 and 2014 that assayed alpha-tocopherol in human milk of healthy women by high performance liquid chromatography were evaluated. The keywords used were "vitamin E", "alpha-tocopherol", "milk, human", "lactation", and equivalents in Portuguese, in the BIREME, CAPES, PubMed, SciELO, ISI Web of Knowledge, HighWire Press, Ingenta, and Brazilian Digital Library of Theses and Dissertations databases. Summary of the findings: Of the 41 publications found on the subject, 25 whose full text was available and met the inclusion criteria were selected. The alpha-tocopherol concentrations found in milk were similar in most populations studied. The variable phase of lactation was shown to influence vitamin E content in milk, which is reduced until the mature milk appears. Maternal variables parity, anthropometric nutritional status, socioeconomic status, and habitual dietary intake did not appear to affect the alpha-tocopherol levels in milk. However, the influence of the variables maternal age...

Supplementation with the omega-3 docosahexaenoic acid: influence on the lipid composition and fatty acid profile of human milk

Bortolozo,Eliana Aparecida Fagundes Queiroz; Sauer,Elenise; Santos,Marli da Silva; Baggio,Sueli Regina; Santos Junior,Guataçara dos; Farago,Paulo Vitor; Cândido,Lys Mary Bileski; Pilatti,Luiz Alberto
Fonte: Pontifícia Universidade Católica de Campinas Publicador: Pontifícia Universidade Católica de Campinas
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/02/2013 Português
Relevância na Pesquisa
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OBJECTIVE: This study assessed the impact of supplementing the diet of women during pregnancy and lactation with fish oil containing the omega-3 fatty acid docosahexaenoic acid, and its influence on the composition of human milk. METHODS: The sample comprised 60 women aged 18 to 38 years with appropriate dietary pattern, all of them healthy and nonsmokers. The intervention consisted of a daily supplementation with fish oil capsules that corresponded to a daily intake of 315mg of docosahexaenoic acid and 80mg of eicosapentaenoic acid during the third trimester of pregnancy and the first three months postpartum. The total fat content and fatty acid profile of their milk were determined by creamatocrit and gas chromatography. Descriptive statistics were used for data analysis and the significance level was set at p<0.05. RESULTS: There was no statistical difference between the fat contents of the study (fish oil capsules) and control (capsules containing corn starch as filler) groups. However, the milk of women taking fish oil contained higher docosahexaenoic and eicosapentaenoic acid levels 30 and 60 days after delivery. These results demonstrate that high omega-3 intake can influence its concentration in human milk. CONCLUSIONS: Given the importance of docosahexaenoic acid in the neonatal period...

Growth of very low birth weight infants fed with milk from a human milk bank selected according to the caloric and protein value

Aprile,Marisa Matta; Feferbaum,Rubens; Andreassa,Nerli; Leone,Claudio
Fonte: Faculdade de Medicina / USP Publicador: Faculdade de Medicina / USP
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/06/2010 Português
Relevância na Pesquisa
47.47979%
OBJECTIVE: To describe growth and clinical evolution of very low birth weight infants fed during hospital stay with milk from a human milk bank according to the caloric-protein value. METHOD: Forty very low birth weight infants were included: 10 were fed milk from their own mothers (GI), and 30 were fed human milk bank > 700 cal/L and 2 g/dL of protein. Growth curves were adjusted using nonlinear regression to the measured growth parameters. RESULTS: full enteral diet was reached in 6.3 days by GI and in 10.8 by GII; a weight of 2 kg was reached in 7.3 weeks for GI and in 7.8 for GII. In GI, 3/10 (33.3%) and in GII, 7/30 (23.3%) developed sepsis. Necrotizing enterocolitis did not occur in GI, but in 3/30 (10.0%) in GII. GI presented with urinary calcium > 4 mg/L in 1/10 (10.0%), urinary phosphorus (Pu) <1 mg/L in 10/10 (100%), and Ca/Cr >0.6 ratio in 1/10 (10.0%) of the cases; in GII, no children presented alterations of the urinary calcium or the Ca and Cr ratio, and Pu was <1 mg/L in 19/30 (63.3%). In terms of growth the 50th percentile for GI was a weight gain of 12.1 g/day (GI) vs. 15.8 g/day (GII), a length gain of 0.75 cm/week (GI) vs. 1.02 cm/week (GII), and a head circumference gain of 0.74 cm/week (GI) vs. 0.76 cm/week (GII). CONCLUSIONS: Human milk bank allowed a satisfactory growth and good clinical evolution for very low birth weight infants.

Suplemento homologo do leite humano acrescido ao leite humano de banco para alimentação do recém-nascido de muito baixo peso

Serafin, Paula de Oliveira
Fonte: Universidade Federal de Mato Grosso do Sul Publicador: Universidade Federal de Mato Grosso do Sul
Tipo: Dissertação de Mestrado
Português
Relevância na Pesquisa
47.533374%
O leite humano não modificado por apresentar uma enorme variabilidade nutricional seja por estágio da lactação, período do dia, paridade, ingesta materna, método de estocagem, armazenamento e administração tem se mostrado inadequado para alimentar o RNPT. A utilização de aditivos de origem bovina promove melhoria dos índices de crescimento em detrimento do perfil dos aminoácidos séricos e incidência de distúrbios gastrintestinais como enterocolite necrosante. Objetivo: Desenvolver, um composto lácteo a partir de leite humano de banco modificado, através do desnate, evaporação e retirada da lactose para ser utilizado na alimentação do recém-nascido pré-termo de muito baixo peso.Método: Foram utilizadas 20 amostras de pool de leite humano divididas em duas alíquotas para compor os dois grupos do estudo: leite humano modificado pelo desnate, evaporação e retirada da lactose (LHM) e leite humano acrescido de aditivo comercial FM85® (LHF). A comparação entre as variáveis mensuradas nas dietas propostas foi realizada por meio do teste paramétrico t-student pareado de uma amostra. A análise estatística foi utilizado a média e o erro padrão da média para todos os resultados que foram analisados estatisticamente utilizando o Microsoft Excel 2003 para planilhamento dos dados e o ―software‖ SigmaStat para Windows...

Cytokine production by human milk cells and peripheral blood mononuclear cells from the same mothers

Hawkes, J.; Bryan, D.L.; Gibson, R.
Fonte: Kluwer Academic/plenum Publ Publicador: Kluwer Academic/plenum Publ
Tipo: Artigo de Revista Científica
Publicado em //2002 Português
Relevância na Pesquisa
47.454897%
Samples of milk (n=80) and venous blood were collected at 5 weeks postpartum from 82 lactating mothers. Human milk cells and peripheral blood mononuclear cells were isolated and the production of interleukin-1β, interleukin-6, and tumor necrosis factor-α in the absence and presence of lipopolysaccharide was determined by enzyme-linked immunosorbent assay. Human milk cells spontaneously produced significantly less interleukin-1β, interleukin-6, and tumor necrosis factor-α than peripheral blood mononuclear cells in the absence of stimulation. In vitro stimulation of human milk cells with lipopolysaccharide (500 ng/ml) for 24 hr increased cytokine production by approximately 40–50%, whereas peripheral blood mononuclear cells responded to lipopolysaccharide (200 ng/ml) with increased cytokine production of up to 350%. These observations suggest that cells in milk are capable of active involvement in the production of the interleukin-1β, interleukin-6, and tumor necrosis factor-α in the mammary gland and have the capacity to respond to further stimulation after leaving the breast.; Joanna S. Hawkes, Dani-Louise Bryan and Robert A. Gibson

Effect of cooked and raw egg consumption on ovalbumin content of human milk: a randomized, double-blind, cross-over trial

Palmer, D.; Gold, M.; Makrides, M.
Fonte: Blackwell Science Ltd Publicador: Blackwell Science Ltd
Tipo: Artigo de Revista Científica
Publicado em //2005 Português
Relevância na Pesquisa
47.365312%
Background Maternal avoidance of egg intake has been recommended to treat egg allergy in breastfed infants. Objective To determine if the concentration of ovalbumin (OVA) in human milk is directly related to the quantity and form of egg consumed by breastfeeding mothers. Methods Randomized, blinded, cross-over, intervention trial. Breastfeeding women (n=41) attended four clinic days between 11 and 14 weeks of lactation and on each day were randomly allocated to receive a test breakfast, identical except for the egg content (no egg, one raw egg, half a cooked egg or one cooked egg). Breast milk samples were collected at two hourly intervals for 8 h and their OVA concentration measured by ELISA. Results There was a direct, dose–response between the amount of cooked egg ingested and the peak OVA concentration (no egg 0.05 ng/mL [95% confidence interval (CI), 0.01–0.11], half a cooked egg 2.24 ng/mL [95% CI, 0.57–3.91], one cooked egg 3.16 ng/mL [95% CI, 1.41–4.91], n=41, P<0.05) as well as the total OVA excretion (no egg 0.18 ng/mL/h [95% CI, 0.04–0.39], half a cooked egg 4.93 ng/mL/h [95% CI, 1.40–8.46], one cooked egg 9.14 ng/mL/h [95% CI, 4.25–14.03], n=41, P<0.05). The peak concentration and total OVA excretion in response to one raw egg did not differ from ingesting half a cooked egg. There was no detectable OVA in the breast milk of 24% (10/41) women up to 8 h after any egg challenge. Conclusion OVA was detected in the breast milk of lactating women up to 8 h after a controlled intake of egg. A dose–response correlation was indicated. As excretion of OVA in human milk appears to be a normal phenomenon...

Long-chain polyunsaturated fatty acids in breast milk: are they essential?

Gibson, R.; Makrides, M.
Fonte: Kluwer Academic / Plenum Publ Publicador: Kluwer Academic / Plenum Publ
Tipo: Artigo de Revista Científica
Publicado em //2001 Português
Relevância na Pesquisa
47.35978%
The need for long-chain polyunsaturated fatty acids (LC-PUFA), such as docosahexaenoic acid (DHA, C22:6n3) and arachidonic acid (AA, C20:4n6), in the diet of infants in order to achieve full developmental potential is a matter of intense investigation by several research groups worldwide. It has been widely reported that breast-fed infants perform better on tests that assess neurodevelopmental outcomes than do formula-fed infants. Although human milk contains LC-PUFA that are absent from formula, it is necessary to demonstrate that any beneficial effects of human milk on infant development are purely attributed to the presence of LC-PUFA in human milk and their absence from formula to establish causality. The hypothesis that dietary DHA is associated with developmental outcome needs to be plausible; the effect must be consistent, specific, and independent of confounding factors. The hypothesis is certainly plausible. DHA is avidly incorporated and retained in brain cerebral phospholipids, and a most consistent finding has been the lower level of cerebral DHA in the brains of formula-fed infants (receiving no DHA) relative to those fed human milk (receiving DHA). The formula-fed infants in these studies were generally fed formulas with adequate alpha-linolenic acid levels...

Effect of maternal egg consumption on breast milk ovalbumin concentration

Palmer, D.; Gold, M.; Makrides, M.
Fonte: Blackwell Science Ltd Publicador: Blackwell Science Ltd
Tipo: Artigo de Revista Científica
Publicado em //2008 Português
Relevância na Pesquisa
47.37093%
BACKGROUND: Maternal dietary avoidance of egg has been recommended to treat egg allergy in breastfed infants. However, only one of three randomized controlled trials have produced evidence in favour of this recommendation. OBJECTIVE: Our objective was to assess human milk ovalbumin (OVA) concentration after daily maternal ingestion of one cooked egg for 3 weeks. METHODS: Mothers with egg-sensitive, eczematous breastfed infants were randomly allocated to consume one muffin per day containing one egg (egg group, n=16) or a similar egg-free muffin (control group, n=16) for 21 days (Days 3-23). All mothers and infants followed an egg-free diet. Breast milk samples were collected at two hourly intervals for 6 h after eating the test muffins on Days 3, 12 and 23 and breast milk OVA concentration measured. Infant eczema was assessed at the commencement and completion of the trial. RESULTS: Women in the egg group had higher OVA concentrations in breast milk than the control group at all time-points. Within each dietary group, OVA excretion did not change with time. OVA was not detected in breast milk of 25% of women in the egg group. In contrast, infant eczema symptom scores significantly reduced with time for both groups. CONCLUSION: Human milk OVA is related to maternal dietary egg intake...

The efficiency and safety of a higher protein human milk fortifier on growth for preterm human milk-fed infants.

Miller, Jacqueline
Fonte: Universidade de Adelaide Publicador: Universidade de Adelaide
Tipo: Tese de Doutorado
Publicado em //2010 Português
Relevância na Pesquisa
47.55047%
Preterm births represent approximately 8% of births in Australia, and this rate has been increasing over the last decade. Nutrition is a cornerstone of their medical management, yet very premature infants remain difficult to adequately nourish and growth failure is a common consequence of prematurity. Human milk is the preferred feed but has inadequate protein to meet their high requirements and must be fortified. Commercial fortifiers contain conservative amounts of protein and fail to compensate for the fall in the protein content of expressed breast milk over time. This thesis tested the hypothesis that preterm infants fed human milk with a higher protein fortifier (1.4 g/100 mL) would have greater length gain with no metabolic disturbances when compared to infants fed human milk fortified to standard levels (1.0 g protein/100 mL). In a randomised controlled trial infants born <31 weeks gestation, whose mothers intended to provide breast milk for their infants, were randomly allocated to receive either the experimental fortifier containing 1.4 g protein or a fortifier equivalent to standard care, containing 1 g protein. The fortifiers were manufactured specifically for the study and were made isocaloric by adjusting the carbohydrate content. They were identical in appearance and mixing rates and all personnel involved in the trial were blinded to the allocation. Preterm formula was used if breast milk supply was inadequate. The intervention period was from the start of fortification to discharge or the infant’s estimated due date...

Effect of increasing protein content of human milk fortifier on growth in preterm infants born at <31 wk gestation: a randomized controlled trial

Miller, J.; Makrides, M.; Gibson, R.; McPhee, A.; Stanford, T.; Morris, S.; Ryan, P.; Collins, C.
Fonte: Amer Soc Clinical Nutrition Publicador: Amer Soc Clinical Nutrition
Tipo: Artigo de Revista Científica
Publicado em //2012 Português
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BACKGROUND: Preterm human milk-fed infants often experience suboptimal growth despite the use of human milk fortifier (HMF). The extra protein supplied in fortifiers may be inadequate to meet dietary protein requirements for preterm infants. OBJECTIVE: We assessed the effect of human milk fortified with a higher-protein HMF on growth in preterm infants. DESIGN: This is a randomized controlled trial in 92 preterm infants born at <31 wk gestation who received maternal breast milk that was fortified with HMF containing 1.4 g protein/100 mL (higher-protein group) or 1.0 g protein/100 mL (current practice) until discharge or estimated due date, whichever came first. The HMFs used were isocaloric and differed only in the amount of protein or carbohydrate. Length, weight, and head-circumference gains were assessed over the study duration. RESULTS: Length gains did not differ between the higher- and standard-protein groups (mean difference: 0.06 cm/wk; 95% CI: -0.01, 0.12 cm/wk; P = 0.08). Infants in the higher-protein group achieved a greater weight at study end (mean difference: 220 g; 95% CI: 23, 419 g; P = 0.03). Secondary analyses showed a significant reduction in the proportion of infants who were less than the 10th percentile for length at the study end in the higher-protein group (risk difference: 0.186; 95% CI: 0.370...

Cytokines (IL-1β, IL-6, TNF-α, TGF-β1, and TGF-β2) and prostaglandin E₂ in human milk during the first three months postpartum; Cytokines (IL-1beta, IL-6, TNF-alpha, TGF-beta1, and TGF-beta2) and prostaglandin E2 in human milk during the first three months postpartum

Hawkes, J.; Bryan, D.L.; James, M.; Gibson, R.
Fonte: Nature Publishing Group Publicador: Nature Publishing Group
Tipo: Artigo de Revista Científica
Publicado em //1999 Português
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47.307446%
Postpartum changes in the concentrations of IL-1beta, IL-6, tumor necrosis factor-alpha (TNF-alpha), transforming growth factor-beta1 (TGF-beta1), TGF-beta2, and prostaglandin E2 in 257 human milk samples collected longitudinally from 49 healthy mothers during the first 12 wk of lactation were determined by ELISA or RIA. The proinflammatory cytokines IL-1beta, IL-6, and TNF-alpha were present in only a proportion of samples, and there was a wide range of concentrations detected at each time in the present study (IL-1beta, <15-400 pg/mL; IL-6, <15-1032 pg/mL; TNF-alpha, <15-2933 pg/mL). Concentrations of prostaglandin E2 increased after the first week and remained elevated for the remainder of the study (range, < 10-9966 pg/mL). The antiinflammatory cytokines TGF-beta1 (range, 43-7108 pg/mL) and TGF-beta2 (range, 208-57935 pg/mL) were present in substantial quantities in all samples, and there was little change in the mean concentration during 12 wk of lactation. The present study shows that immunomodulating agents are normally present in human milk in physiologically relevant quantities for at least the first 3 mo of the breast-fed infant's life.; Joanna S Hawkes ; Dani-louise Bryan ; Michael J James ; Robert A Gibson

Serum phenylalanine in preterm newborns fed different diets of human milk,

Thomaz,Débora M.; Serafin,Paula O.; Palhares,Durval B.; Tavares,Luciana V.M.; Grance,Thayana R.S.
Fonte: Sociedade Brasileira de Pediatria Publicador: Sociedade Brasileira de Pediatria
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/10/2014 Português
Relevância na Pesquisa
47.61944%
Objective:To evaluate phenylalanine plasma profile in preterm newborns fed different human milk diets.Methods:Twenty-four very-low weight preterm newborns were distributed randomly in three groups with different feeding types: Group I: banked human milk plus 5% commercial fortifier with bovine protein, Group II: banked human milk plus evaporated fortifier derived from modified human milk, Group III: banked human milk plus lyophilized fortifier derived from modified human milk. The newborns received the group diet when full diet was attained at 15 ± 2 days. Plasma amino acid analysis was performedon the first and last day of feeding. Comparison among groups was performed by statistical tests: one way ANOVA with Tukey's post-test using SPSS software, version 20.0 (IBM Corp, NY, USA), considering a significance level of 5%.Results:Phenylalanine levels in the first and second analysis were, respectively, in Group I: 11.9 ± 1.22 and 29.72 ± 0.73; in Group II: 11.72 ± 1.04 and 13.44 ± 0.61; and in Group III: 11.3 ± 1.18 and 15.42 ± 0.83 μmol/L.Conclusion:The observed results demonstrated that human milk with fortifiers derived from human milk acted as a good substratum for preterm infant feeding both in the evaporated or the lyophilized form...

Nutrient-enriched formula milk versus human breast milk for preterm infants following hospital discharge

Henderson, Ginny; Fahey, Tom; McGuire, William
Fonte: The Cochrane Library Publicador: The Cochrane Library
Tipo: Artigo de Revista Científica
Português
Relevância na Pesquisa
47.34603%
Background: Preterm infants are often growth-restricted at hospital discharge. Feeding infants after hospital discharge with nutrient-enriched formula milk instead of human breast milk might facilitate "catch-up" growth and improve development. Objectives

HUMAN MILK BANK: THE BREASTFEEDING COUNSELING AND THE DURATION OF EXCLUSIVE BREASTFEEDING

Figueiredo, Maria Claudia Diniz; Bueno, Márcia Penna; Ribeiro, Camila Cury; Lima, Patrícia Azevedo; Silva, Ísis Tande
Fonte: Universidade de São Paulo. Faculdade de Saúde Pública Publicador: Universidade de São Paulo. Faculdade de Saúde Pública
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; ; ; ; Formato: application/pdf; application/pdf
Publicado em 20/10/2015 Português
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47.35978%
Objective: To identify which sociodemographic factors are associated with early weaning and compare the duration of exclusive breast feeding between mothers which received counseling about maternal feeding and mothers which was not guided for these practices. Methods: A cross-sectional study with 25 mothers that received counseling about the benefits of maternal feeding in the human milk bank and 25 from a university hospital that were not counseled. Data were collected using a structured questionnaire addressing mother-related data, the infant and the breastfeeding in the first semester. Comparison and odds ratio were the statistical analyses adopted. Results: There was not a significant difference of the duration of exclusive breast-feeding between the two groups (p = 0,524). Among mothers in the human milk bank group that discontinued early exclusive breast-feeding, fewer children (p=0,034) and a higher frequency of maternal work (p = 0,022) were observed. Wile, in the university hospital group low education (p < 0.001) and lower income (p = 0.009) were prevalent. In the totality of the sample, the interruption of exclusive breast-feeding was associated with <1 children (OR = 0.21, p = 0.030), the presence of a partner (OR = 0.046...

Growth of very low birth weight infants fed with milk from a human milk bank selected according to the caloric and protein value

Aprile, Marisa Matta; Feferbaum, Rubens; Andreassa, Nerli; Leone, Claudio
Fonte: Universidade de São Paulo. Faculdade de Medicina Publicador: Universidade de São Paulo. Faculdade de Medicina
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; ; ; ; ; Formato: application/pdf
Publicado em 01/06/2010 Português
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OBJECTIVE: To describe growth and clinical evolution of very low birth weight infants fed during hospital stay with milk from a human milk bank according to the caloric-protein value. METHOD: Forty very low birth weight infants were included: 10 were fed milk from their own mothers (GI), and 30 were fed human milk bank > 700 cal/L and 2 g/dL of protein. Growth curves were adjusted using nonlinear regression to the measured growth parameters. RESULTS: full enteral diet was reached in 6.3 days by GI and in 10.8 by GII; a weight of 2 kg was reached in 7.3 weeks for GI and in 7.8 for GII. In GI, 3/10 (33.3%) and in GII, 7/30 (23.3%) developed sepsis. Necrotizing enterocolitis did not occur in GI, but in 3/30 (10.0%) in GII. GI presented with urinary calcium > 4 mg/L in 1/10 (10.0%), urinary phosphorus (Pu)

Qualidade microbiológica de leite humano obtido em banco de leite; Microbiological quality of human milk from a Brazilian milk bank

Serafini, Álvaro B; André, Maria Cláudia D P B; Rodrigues, Márcia A V; Kipnis, André; Carvalho, Cynthia O; Campos, Maria Raquel H; Monteiro, Érica C; Martins, Fábia; Jubé, Thiago F N
Fonte: Universidade de São Paulo. Faculdade de Saúde Pública Publicador: Universidade de São Paulo. Faculdade de Saúde Pública
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; ; ; ; Formato: application/pdf
Publicado em 01/12/2003 Português
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OBJETIVO: Determinar a prevalência de microrganismos indicadores e potencialmente patogênicos que indicam as condições higiênico-sanitárias das amostras de leite humano ordenhado coletadas em banco de leite. MÉTODOS: Foram realizadas análises microbiológicas de 338 amostras de leite humano ordenhado, sendo 194 de leite cru e 144, pasteurizado, coletadas em banco de leite humano de um hospital materno infantil de Goiânia, GO. As análises microbiológicas foram realizadas com semeadura em ágar Mc Conkey, de acordo com o tipo de bactéria. RESULTADOS: No leite cru, verificou-se a presença de Staphylococcus spp. Streptococcus spp., bolores e leveduras e Enterobacteriaceae. Observou-se que Staphylococcus aureus esteve presente em 10 (5,2%) amostras, Staphylococcus epidermidis em 28 (14,4%), Streptococcus spp. em três (1,6%), bolores e leveduras em 43 (22,2%) e Enterobacteriaceae em 49 (25,3%). Das 144 amostras de leite humano ordenhado pasteurizado, detectaram-se Staphylococcus aureus em cinco (3,5%), Staphylococcus epidermidis em 15 (10,4%), Staphylococcus lugdenensis em duas (1,4%), Streptococcus spp. em quatro (2,8%), bolores e leveduras em 37 (25,7%) e Enterobacteriaceae em nove (6,3%). CONCLUSÕES: Os resultados mostraram um alto grau de contaminação no leite cru. No leite pasteurizado...